Product ID:STREPTOMYCIN SULFATE, STREPTOMYCES SP, 5711
MSDS Date:06/09/1999
FSC:6550
NIIN:00N092492
Status Code:A
MSDS Number: CJSPH

Emergency Phone: 800-424-9300

Info Phone: 800-854-3417

Cage: 29089

Telephone: 619-450-5558; 800-854-3417

Cage: 29089

STREPTOMYCIN SULFATE

CAS: 3810-74-0

RTECS: WK4990000

LD50 LC50 Mixture:LD50: (ORAL,RAT) 430 MG/KG
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: MAY BE HARMFUL BY INGESTION,
INHALATION OR ABSORPTION THROUGH SKIN. EXPOSURE TO MATERIAL MAY
CAUSE FOLLOWING: HYPERSENSITIVITY IF INHALED, VERTIGO, TINNITUS,
DEAFNESS, AND RESPIRATORY EFFECTS. CHRONIC: THERE IS LIMITED
EVIDENCE THAT STREPTOMYCIN SULFATE IS TERATOGENIC. UNTIL FURTHER
TESTING HAS BEEN DONE, IT SHOULD BE TREATED AS A POSSIBLE TERATOGEN
IN HUMANS.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:IN CASE OF SKIN CONT, WASH W/COPIOUS AMTS OF WATER FOR AT LST
15 MINS. REMOVE CONTAMD CLTHG & SHOES & WASH BEFORE WEARING.
CONSULT PHYSICIAN. IN CASES OF EYE CONT, FLUSH W/COPIOUS AMTS OF
WATER FOR AT LST 15 MINS. ASSURE ADEQ FLUSHING BY SEPARATING
EYELIDS W/FINGERS. CONSULT PHYSICAN. IN CASES OF INHALATION, REMOVE
TO FRESH AIR & MONITOR BRTHG. IF BRTHG BECOMES DFCLT, GIVE OXYG &
CONSULT PHYSICIAN . IF BRTHG STOPS, GIVE ARTF RESP & CONSULT
PHYSICIAN. IN CASES OF INGESTION, WASH MOUTH OUT W/WATER & CONSULT
LOCAL POISON CENTER AND PHYSICIAN.

Autoignition Temp:Autoignition Temp Text:NP
Extinguishing Media:DRY CHEMICAL POWDER, CARBON DIOXIDE, WATER SPRAY,
ALCOHOL OR POLYMER FOAM.
Fire Fighting Procedures:WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS AND FULL PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN
AND EYES.
Unusual Fire/Explosion Hazard:UPON THERMAL DECOMPOSITION, IT MAY EMIT
TOXIC GASES.

Spill Release Procedures:EVACUATE AREA. WEAR NIOSH APPRVD RESP, CHEM
SAFETY GOGGLES, RUBBER BOOTS, AND HEAVY RUBBER GLOVES. SWEEP UP AND
PLACE IN SUITABLE CONTAINER. AVOID RAISING DUST. HOLD FOR
APPROPRIATE DISPOSAL. WASH SPI LL SITE AND VENTILATE AREA AFTER
MATERIAL PICKUP IS COMPLETE.

Handling and Storage Precautions:STORE IN TIGHTLY CLOSED CONTAINER IN A
COOL, DRY PLACE (+20C). MATERIAL IS HARMFUL. POSSIBLE TERATOGEN.
AVOID CONTACT WITH MATERIAL. AVOID PROLONGED OR REPEATED EXPOSURE.
Other Precautions:LAB SHOULD BE EQUIPPED WITH SAFETY SHOWER AND AN EYE
WASH STATION. WASH THOROUGHLY AFTER HANDLING MATERIAL.

Respiratory Protection:USE A NIOSH APPROVED RESPIRATOR.
Ventilation:HANDLE IN A CHEMICAL FUME HOOD WITH ADEQUATE VENTILATION.
Protective Gloves:CHEMICAL RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EYE WASH & DELUGE SHOWER .
WEAR SUITABLE PROTECTIVE CLOTHING.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING MATERIAL.
Supplemental Safety and Health
TOX INFO: ARZNEIMITTEL-FORSCHUNG. DRUG RESEARCH. 12, 597. SCU;MUS;LD50:
403 MG/KG 1956/1957. ANTIBIOTICS ANNUAL. 4,574. REPRO EFTS &
REFERENCES: ORL/RAT;DOSE: 37 G/KG TOXIC EFTS ON FEMALE FERTILITY &
NEWBORN GROWTH STATISTICS 1979. OYO YAKURI. PHARMACOMETRICS. 17,
109. IMS;WMN;DOSE: 1700 MG/KG (OTHER INFO)

Solubility in Water:SOLUBLE
Appearance and Odor:WHITE SOLID.

Stability Indicator/Materials to Avoid:YES
NOT APPLICABLE.
Stability Condition to Avoid:STABLE UNDER NORMAL HANDLING PROCEDURES.
Hazardous Decomposition Products:UPON THERMAL DECOMPOSITION, MAY EMIT
TOXIC GASES INCLUDING CARBON MONOXIDE, CARBON DIOXIDE, NITROGEN
OXIDES, AND SULFUR OXIDES.

Waste Disposal Methods:COUNTRY, FEDERAL, STATE, AND LOCAL REGULATIONS
ARE VARIED AND CHANGE FREQUENTLY. OR THIS REASON, WE RECOMMEND THAT
YOU CONTACT YOUR LOCAL DEPARTMENT OF HEALTH SERVICES FOR INFO ON
DISPOSAL OF THIS PRO DUCT OR ARRANGE FOR DISPOSAL BY LICENSED
DISPOSAL COMPANY.

Toxicological Information:RTECS: WK4990000. TOX DATA & REFERENCES:
ORL;RAT;LD50: 430 MG/KG 1982. 'TOXICOMETRIC PARAMETERS OF
INDUSTRIAL TOXIC CHEMS UNDER SINGLE EXPOS.' -, 106. ORL;MUS;LD50:
430 MG/KG 1982. 'TOXICOMETRIC PARAM ETERS OF INDUSTRIAL TOXIC CHEMS
UNDER SINGLE EXPOS.' -, 106. ORL;HAM;LD50: 400 MG/KG DEPRESSED
ACTIVITY; DIARR 1969. TOXICOLOGY & APPLIED PHARMACOLOGY. 14, 510.
IPR;INF;TDLO: 170 MG/KG FLACCID PARALYS IS; CHANGE IN MOTOR
ACTIVITY; RESP CHANGES 1961. BRITISH MED JOURNAL. 1, 557,
IVN;MUS;LD50: 90200 UG/KG 1973. ANTIBIOTLKI. 18, 444. SCU;RAT;LD50:
600 MG/KG 1962. (SUPDAT)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:NO INFORMATION FOUND.

Transport Information:UN NUMBER: N/A. PROPER SHIPPING NAME: N/A. IATA
CLASS: N/A. IATA PACKING GROUP: N/A.

Federal Regulatory Information:XN. RISK PHRASES: R20/21/22: HARMFUL BY
INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED. R40: POSSIBLE
RISK OF IRREVERSIBLE EFFECTS. SAFETY PHRASES : S22: DO NOT BREATH
DUST. S24/25: AVOID CONTACT W ITH SKIN AND EYES. S36/37/39: WEAR
SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE PROTECTION. S45:
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY.
State Regulatory Information:OTHER INFO: AVOID PROLONGED OR REPEATED
EXPOSURE. WASH THOROUGHLY AFTER HANDLING MATERIAL SHOULD ONLY BE
HANDLED BY QUALIFIED, EXPERIENCED PROFESSIONALS.